Nano-hydroxyapatite/natural polymer composite scaffolds for bone tissue engineering: a brief review of recent trend

Nanostructured inorganic biomaterial emerged as the most essential platform to address traumatic and non-traumatic conditions of hard tissues in current scenario. Synthetic biomaterials serve an efficient pathogen-free choice that overcomes obstructions associated with autografts allografts promote new tissue regeneration, since nano-hydroxyapatite (nHAp) is a mimics natural mineral composition bones teeth human tissues, which widely employed orthopedics dentistry. The nHAp-based materials exhibit bioactive, biocompatible, osteoconductive features under vitro vivo conditions. brittle nature synthetic nHAp leads weak mechanical properties, eventually confines utility load-bearing applications. Hence, this review focuses on recent trends fabrication investigation polymer nanocomposite scaffolds for bone regeneration. Employing different polymers strategies would efficiently tailor physicochemical tailor-made properties competence biodegradation, thereby enhancing their potential biomedical utility, exploring efficacy make “HAp-based smart-biomaterials” engineering.